Factors affecting time to maintenance dose in patients initiating warfarin
نویسندگان
چکیده
منابع مشابه
Factors determining the maintenance dose of warfarin in Chinese patients.
Chinese patients are reportedly more sensitive than Caucasians to the anticoagulant effect of warfarin. We examined warfarin dose requirements and their determinants in 151 Chinese out-patients on stable maintenance dose of warfarin with international normalized ratio of 2 to 2.5. Mean daily warfarin requirement was 3.3 +/- 1.4 mg, much lower than reported doses in Caucasian patients. The most ...
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The effects of genetic variants on warfarin dosing vary among different ethnic groups, especially in the Chinese population. The objective of this study was to recruit patients through a rigorous experimental design and to perform a comprehensive screen to identify gene polymorphisms that may influence warfarin dosing in northern Han Chinese patients with mechanical heart valve replacement. Con...
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Warfarin is a frequently prescribed anticoagulant in rehabilitation patients. Adverse drug reactions of warfarin were reported as bleeding and cutaneous microvascular thrombosis. Major bleeding, such as intracranial hemorrhage and psoas hematoma, in patients receiving anticoagulation therapy is a rare condition, but sometimes very serious complication that can even be fatal. Patient-specific fa...
متن کاملGenetic factors for warfarin dose prediction.
stolic dysfunction either in asymptomatic or symptomatic patients, that is, stage B or C of the definition of heart failure, according to the classification of the American Heart Association/American College of Cardiology task force for the diagnosis and management of chronic heart failure (3 ). One important finding of our metaanalysis (1 ) is represented by the heterogeneity of data published...
متن کاملWarfarin maintenance dose in Iranian patients. A cross sectional study in 5 cities of Iran.
OBJECTIVE To determine the warfarin maintenance dose in Iranian patients. METHODS This multicenter study was conducted between January 2007 and January 2008 in 5 different large cities of Iran. Patients older than 12 years receiving warfarin were included. During the first days of warfarin use, international normalized ration (INR) was measured daily and after that every 1-2 weeks, with a dur...
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ژورنال
عنوان ژورنال: Pharmacoepidemiology and Drug Safety
سال: 2014
ISSN: 1053-8569
DOI: 10.1002/pds.3735